Stenhousemuir's central defender Ross McMillan will return from suspension to face promotion-chasing rivals Airdrie United.
But the Warriors will be without injured pair Eric Paton and Sean Dickson in a game they have got to win.
Assistant manager Kevin McGoldrick said: "This is a big game in our season.
"Airdrie are on a great run just now and have joined ourselves and East Fife in the play-off race, but we have been in a play-off place for virtually the entire season and do not plan on giving it up.
"We went to East Fife last week and came from a goal behind to get a draw and will need to show that same kind of fighting spirit to get something from this one."
Airdrie United will be without experienced defender Paul Lovering as they look to leapfrog Stenhousemuir in the chase for a play-off place.
But the Diamonds will welcome back Graeme Owens, Nathan Blockley, Scott Sally and Scott Morton following injury to give manager Jimmy Boyle plenty of attacking options.
Boyle said: "We've got ourselves into a good position thanks to four wins in a row. Defensively we have looked a lot stronger recently, but we know that will be tested against a Stenhousemuir side that have good strikers in Stewart Kean, Andy Rodgers and Kenny Deuchar.
"Ochilview is a ground where we have not done well or a few seasons and it would be good to put that right."